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In summary, there is a hierarchy of studies from ones that open
up a question to ones that may be the definitive answer, or as
close to that as is possible. With increasing certainty comes
increasing complexity and attention to detail (and increasing
expense, time, and cooperation). Epidemiology is now a large
industry, worldwide, and the successes since World War II have
been very substantial.
For more information on these topics, there are two best-seller
text books available on the web:
Epidemiology for the uninitiated
Statistics at Square one
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