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Finally, the
uterine environment seems to “set” the embryo’s metabolism for what to expect after
birth. In lean times, a poorly nourished mother may produce a baby whose metabolism is set
to be efficient with energy extraction and storage. Fifty years later, if food has been
plentiful, a person’s risk of heart disease, and probably their weight, is much
increased. Similar uterine effects have been proposed for other disease, such as breast
cancer. This model is called Barker’s Hypothesis.
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